Absorbable membranes for GBR procedures

Speaker: Daniel Rothamel

Originally broadcasted on: 20th March, 2018, 6:00 PM CET Other time zones

The principle of guided bone regeneration (GBR) is based on the spatial separation of the bone graft and the overlying connective tissue.


Whereas in the past the intact periosteum was discussed as suitable membrane for GBR procedures, today the application of mechanical barriers in combination with bone grafting materials are highly esteemed. Although decades ago, non-absorbable membranes were considered as gold standard for guided bone regeneration, more and more absorbable collagen membranes were established as barrier membranes over the years. Assessing the variability of the collagen membranes, several differences exist, such as the tissue of origin, the barrier time, the tissue integration and the pattern of the cellular reaction and biodegradation.

Less controversially discussed is the negative influence of the chemical cross-linking of the collagen fibrils with regard to the wound healing process, although it´s known to be related to a delayed resorption process. Hence, new ways of preventing the fast resorption of native collagen are in the focus of the research. This webinar demonstrates the benefits of absorbable membranes with regard to their biocompatibility, barrier function and discusses the importance of an early angiogenesis.


Daniel Rothamel
Daniel RothamelEducation:
  • 1996 - 2001: Dental School, Heinrich-Heine University, Duesseldorf, Germany
  • 2001 - 2007: Medical School, Heinrich-Heine University,Duesseldorf, Germany
  • January 2004: Dr. med. dent., magna cum laude, Thesis: "Establishing a new method for quantification of tooth hypersensitivity"
  • January 2007: Specialization in Oral Surgery
  • October 2008: Dr. med., magna cum laude, Thesis: “Biocompatibility, biodegradation and angiogenetic aspects of native and cross-linked collagen membranes”
Professional Experience:
  • 2002 – 2007: Research Associate, Department of Oral Surgery (Prof. Dr. J. Becker) Heinrich-Heine University, Düsseldorf, Germany.
  • Feb. – Mar. 2005: Volunteer at the Clinic of Plastic and Reconstructive Surgery in Sankhu, Kathmandu, Nepal
  • June – Dec 2007: Post-doc Student at the Department of Oral Pathology and Molecular Research, Westmead Hospital, University of Sydney, Sydney, Australia (granted by DAAD)
  • Since 2008: Research Associate, Department of Oral and Maxillofacial Plastic Surgery (Prof. Dr. Dr. J. Zoeller), University of Cologne, Cologne, Germany
  • 2009: PhD status., Thesis: “Reconstruction of jaw defects using artificial and autogenous bone blocks in combination with growth factors”
Research topics:
  • Guided bone regeneration, implant surfaces, collagen membranes, bone substitute materials, growth factors.

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